NCT04430465

Effects of Wholegrains on Children's Health (KORN)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: University of Copenhagen · Academic / Other
• Sex: All
• Age: 8 Years – 13 Years
• Healthy volunteers: Accepted

Summary

KORN investigates the effects of wholegrain oat and rye intake on health and cognitive wellbeing in children with overweight.

Detailed description

The purpose of KORN is to investigate the effects of wholegrain oat and rye intake on cardiometabolic health in slightly overweight 8-13-year-old children. Moreover, KORN aims to investigate effects on body weight and body composition, inflammatory markers, gastrointestinal wellbeing and cognitive function and explore the potential underlying mechanisms through assessment of changes in the children's gut microbiota as well as potential genotype-dependent and sex-specific effects. The study has a randomized controlled cross-over design. In two 8-week dietary periods the children will receive grain products (cereals, breads, pasta etc) with either high or low content of wholegrain from oat and rye in random order. Measurements and biological sampling will be performed at 0, 8 and 16 weeks.

Conditions

• Cardiometabolic Health
• Gastro-intestinal Wellbeing
• Cognitive Function
• Overweight

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Grain products high in wholegrains from oat and rye	A selection of grainproducts high in wholegrain from oat and rye, including cereals, bread, rolls, and pasta is replacing habitual grain products
DIETARY_SUPPLEMENT	Grain products low in wholegrains	A selection of grainproducts low in wholegrain, including cereals, bread, rolls, and pasta is replacing habitual grain products

Timeline

• Start date: 2020-09-03
• Primary completion: 2021-05-04
• Completion: 2021-05-04
• First posted: 2020-06-12
• Last updated: 2021-05-07

Locations

1 site across 1 country: Denmark