Clinical Trials Directory

Trials / Completed

CompletedNCT04429646

LAMax Vs. Watchman LAAC Device for Subjects With Non-valvular AF to Reduce the Risk of Stroke

A Prospective, Multicenter, Randomized, Active Controlled, Clinical Trial of the LAMax LAA Closure System Compared to the Watchman® LAAC Device for Subjects With Non-valvular Atrial Fibrillation to Reduce the Risk of Ischemic Stroke

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
236 (actual)
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a prospective, multicenter, randomized, active controlled, clinical trial to evaluate the safety and effectiveness of the LAMax Left Atrial Appendage (LAA) Closure System.

Detailed description

This is a prospective, multicenter, randomized, active controlled, clinical trial to evaluate the safety and effectiveness of the LAMax Left Atrial Appendage Closure (LAAC) System. Subjects with non-valvular Atrial Fibrillation will be randomized in a 1:1 ratio to the Experimental Treatment Arm (LAMax LAAC system) or the Control Arm (Watchman LAAC system, Boston Scientific Inc., USA). The trial is designed to demonstrate that safety and effectiveness of the LAMax device are non-inferior to the Watchman device.

Conditions

Interventions

TypeNameDescription
DEVICEPercutaneous left atrial appendage closure-LAMaxInterventional device, LAMax left atrial appendage closure system
DEVICEPercutaneous left atrial appendage closure-WatchmanInterventional device, Watchman® LAA Closure Device

Timeline

Start date
2019-04-20
Primary completion
2020-11-11
Completion
2021-06-10
First posted
2020-06-12
Last updated
2022-05-06

Locations

12 sites across 1 country: China

Source: ClinicalTrials.gov record NCT04429646. Inclusion in this directory is not an endorsement.