NCT04428138

Inguinal Hernia and Arterial Disease

Observational Cross-sectional Study on the Association Between Inguinal Hernias and Arterial Diseases

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: University of Catanzaro · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Inguinal hernias are associated with problems related to the venous system by the linking to extracellular matrix alterations (ECM). On the other hand, arterial diseases (arterial aneurysms, carotid, stenosis, peripheral artery disease) are widespread in the general population and may share others pathological pathways related to ECM impairment. Aim to this study is to evaluate the prevalence of arterial diseases in patients with inguinal hernia.

Detailed description

Previous studies showed the correlation between inguinal hernias and venous disease. The common pathophysiological pathway between these clinical conditions is linked to extracellular matrix (ECM) alterations. Arterial diseases, mainly represented by carotid stenosis, peripheral artery disease and arterial aneurysms, are widespread in western population and are responsible of high rates of morbidity and mortality. These diseases are also related to some ECM alterations. Aim of this cross-sectional study is to evaluate the prevalence of arterial disease among patients with inguinal hernias. The primary endpoint of this study is to provide new epidemiological evidences on this association that may help physicians in novel preventive strategies. The study will consider the inclusion of consecutive patients assessed for inguinal hernia over 1 year period in order to study the prevalence of concomitant arterial disease, by means of office visit, echo duplex scan of the aorta and its main branches, carotid arteries and lower limb arteries.

Conditions

• Inguinal Hernia
• Arterial Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	In-office vascular visit	Every patient will undergo a complete physical examination in order to detect any clinical or sub clinical vascular disease.
DIAGNOSTIC_TEST	Echo duplex scan of arterial system	Every patient will undergo a complete echo duplex scan in order to detect any morphological or hemodynamic alteration of aorta, carotid arteries and lower limb arteries.

Timeline

• Start date: 2020-06-01
• Primary completion: 2021-06-01
• Completion: 2021-07-01
• First posted: 2020-06-11
• Last updated: 2020-06-11

Locations

2 sites across 1 country: Italy