Trials / Completed
CompletedNCT04426994
Hypomagnesemia Associated With Proton-Pump Inhibitor Use
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 211,672 (actual)
- Sponsor
- Changi General Hospital · Academic / Other
- Sex
- All
- Age
- 14 Years – 100 Years
- Healthy volunteers
- —
Summary
Use of proton pump inhibitors has been associated with hypomagnesemia. However, various case-control or prospective studies have found conflicting results with regards to proton pump inhibitors use and development of hypomagnesemia. Our aim was to evaluate the likelihood that proton pump inhibitors contributed to severe hypomagnesemia in a retrospective cohort of patients admitted with severe hypomagenesemia. We also aimed to look for risk factors leading to development of hypomagnesemia amongst users of proton pump inhibitors
Conditions
- Proton Pump Inhibitor Adverse Reaction
- Hypomagnesemia
- Arrhythmias, Cardiac
- Seizures
- Hypocalcemia
- Hypokalemia
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | proton pump inhibitor use | Patients using long term proton pump inhibitor |
Timeline
- Start date
- 2017-01-31
- Primary completion
- 2018-01-30
- Completion
- 2019-09-30
- First posted
- 2020-06-11
- Last updated
- 2020-06-11
Locations
1 site across 1 country: Singapore
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT04426994. Inclusion in this directory is not an endorsement.