Clinical Trials Directory

Trials / Unknown

UnknownNCT04425876

A Study of Fluzoparib in Combination With mFOLFIRINOX in Patients With Resectable Pancreatic Cancer

A Phase I Study to Assess the Tolerability, Safety and Efficacy of Fluzoparib in Combination With mFOLFIRINOX as Neoadjuvant and Adjuvant Therapy in Patients With Resectable Pancreatic Cancer

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
74 (estimated)
Sponsor
Jiangsu HengRui Medicine Co., Ltd. · Industry
Sex
All
Age
18 Years – 79 Years
Healthy volunteers
Not accepted

Summary

The study is being conducted to: a) evaluate the tolerability and safety of the co-administration of Fluzoparib and FOLFIRINOX in patients with resectable pancreatic cancer, and establish a maximum tolerated dose and recommended phase II dose of the combination and b) assess the efficacy of the co-administration of Fluzoparib and FOLFIRINOX in patients with resectable pancreatic cancer.

Conditions

Interventions

TypeNameDescription
DRUGFluzoparibFluzoparib combined with mFOLFIRINOX followed by maintenance Fluzoparib monotherapy

Timeline

Start date
2020-12-17
Primary completion
2023-03-01
Completion
2023-09-01
First posted
2020-06-11
Last updated
2020-12-31

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04425876. Inclusion in this directory is not an endorsement.