Clinical Trials Directory

Trials / Completed

CompletedNCT04422509

Lanadelumab for Treatment of COVID-19 Disease

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
43 (actual)
Sponsor
Radboud University Medical Center · Academic / Other
Sex
All
Age
16 Years
Healthy volunteers
Not accepted

Summary

So far little is very few drugs have demonstrated positive results for treatment of COVID19. Recently the researchers have shown that the use of icatibant in COVID-19 results in a potent decrease in oxygen use. Yet the effect of the three dosages as according to the label dose was insufficient to maintain the clinical improvement in a small group of patients. The researchers argue that with the use of lanadelumab a more lasting effect can be reached due to its longer half life.

Conditions

Interventions

TypeNameDescription
BIOLOGICALlanadelumabsingle dose, or two doses administered iv
OTHERregular careno lanadelumab administration, treated according to regular care

Timeline

Start date
2020-10-30
Primary completion
2021-02-25
Completion
2021-04-30
First posted
2020-06-09
Last updated
2021-07-13

Locations

4 sites across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT04422509. Inclusion in this directory is not an endorsement.