Trials / Unknown
UnknownNCT04421469
Triprilimab(JS001) and Chemotherapy Combined With Local Treatment for Multiple Metastatic NPC
A Single-arm, Open Multicenter Phase II Clinical Study of Triprilimab(JS001) and Chemotherapy Combined With Local Treatment for Multiple Metastatic NPC
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 39 (estimated)
- Sponsor
- Fujian Cancer Hospital · Other Government
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
This study is a randomized, phase II, prospective, multicenter clinical trial to evaluate the efficacy and tolerability of JS001 and chemotherapy combined with local treatment in patients with multiple metastatic nasopharyngeal carcinoma.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Triprilimab(JS001) | 1. JS001 240mg d1, gemcitabine(1g/m²),d1,8 + nedaplatin (80-100mg/m²),d2,q3w,6cycles.The curative effect was evaluated every 2 cycles.If the therapeutic evaluation was SD,the chemotherapy scheme was changed; 2. Local treatment of active lesions(including radiotherapy and/or radiofrequency ablation); 3. JS001 maintenance treatment. |
Timeline
- Start date
- 2020-06-15
- Primary completion
- 2023-04-15
- Completion
- 2023-06-15
- First posted
- 2020-06-09
- Last updated
- 2020-06-09
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04421469. Inclusion in this directory is not an endorsement.