NCT04419831

Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive Learning and Executive Function

Characterizing Subjective and Physiological Responses to Stress and Pain and Cognitive

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 81 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The study design is to assess the between groups factor (controls, chronic pain, addicted individuals) and repeated measures factor of pain/stress (pain vs no pain) along with a longitudinal component to assess stress, pain and addictive behaviors in daily life.

Detailed description

This proposal aims to systematically examine the physiologic, neuroendocrine and behavioral stress and pain responses to an adapted Cold Pressor Test and also assess specific cognitive and executive function tests in community volunteers with a history of stress and trauma, social users of alcohol, cannabis and individuals with alcohol use disorder, cannabis use disorder, opioid use disorder, cocaine use disorder and chronic pain.

Conditions

• Pain Response, Stress, Trauma

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Yale Stress Pain Test (YSPT)	Yale Stress Pain Test involves 10 minutes exposure to 3 cycles of ice cold bucket hand immersion (stress) or 3 cycles of warm water immersion

Timeline

• Start date: 2022-04-14
• Primary completion: 2023-12-30
• Completion: 2023-12-30
• First posted: 2020-06-05
• Last updated: 2024-02-07

Locations

1 site across 1 country: United States