Clinical Trials Directory

Trials / Completed

CompletedNCT04419636

Binding of Lu AG06466 in the Brain in Healthy Men

Interventional, Open-label, Position Emission Tomography (PET) Study Investigating MAGL Occupancy After Single and Multiple Oral Doses of Lu AG06466 in Healthy Male Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
16 (actual)
Sponsor
H. Lundbeck A/S · Industry
Sex
Male
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

A study to learn how Lu AG06466 and one of its break down products binds in the brain after single and repeated dosing

Detailed description

The study will be conducted in two Parts. Part A: cross over, fed/fasted determined by randomized sequence Part B: sequential group PET scans will be used to quantify MAGL occupancy

Conditions

Interventions

TypeNameDescription
DRUGLu AG06466capsules, orally

Timeline

Start date
2020-05-29
Primary completion
2021-02-09
Completion
2021-02-16
First posted
2020-06-05
Last updated
2021-02-24

Locations

1 site across 1 country: Belgium

Source: ClinicalTrials.gov record NCT04419636. Inclusion in this directory is not an endorsement.