NCT04418869

Exercise in Adolescents With Type 1 Diabetes

Metabolic Effects of Exercise in Adolescents With Type 1 Diabetes

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Region Örebro County · Academic / Other
• Sex: Male
• Age: 16 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

Regular physical activity is an important part of diabetes management in adolescents with type 1 diabetes (T1D). Increased physical activity has several beneficial effects such as improved lipid profile, insulin sensitivity and quality of life. In addition, a reduced HbA1c is often seen in association to increased physical activity. However, the effect on glycemic control and the acute glycemic response seems to differs between different types of exercise. This issue is poorly studied in adolescents with T1D and the mechanism behind this is not fully understood. The primary aim of this study was to compare the acute effects on glycemia of resistance and two aerobic continuous and intermittent exercise bouts in adolescents with type 1 diabetes. Secondarily, the investigators want to compare the different exercise according to hormonal changes and expression of mRNA in muscle. At a baseline visit the participants was tested for maximal oxygen consumption (pVO2peak) and maximal strength (1-RM). The study participants then performed three exercise bouts and one control session (resting), each on 45 minutes, in a randomized order. Measurement was performed during and after the exercise.

Conditions

• Type 1 Diabetes

Interventions

Type	Name	Description
OTHER	Exercise bouts	Each subject performed three bouts with 45 minutes of exercise (continuous exercise, intermittent exercise and resistance exercise) in a randomized order. In addition a control session were performed where the subjects sat on a chair for 45 minutes.

Timeline

• Start date: 2014-03-01
• Primary completion: 2016-06-27
• Completion: 2024-06-01
• First posted: 2020-06-05
• Last updated: 2022-10-31