Trials / Unknown
UnknownNCT04414735
Impact of Photopheresis in the Prevention of Acute Rejection in Highly Sensitized de Novo Kidney Transplant Recipients
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the present study is to evaluate the superiority of photopheresis in combination with the standard immunosuppression vs standard immunosuppression alone for the prevention of acute rejection in highly sensitized kidney transplant recipients (cPRA ≥90%). Unicentric, randomized, open study.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Extracorporeal Photopheresis | Infusion of autologous cellular products exposed to ultraviolet light (UV), in the presence of a photosensitizer. The cellular product is obtained through leucopheresis and its subsequent exposure to 8-methoxypsoralen (8-MOP) and irradiation with UV-A light. |
Timeline
- Start date
- 2022-08-17
- Primary completion
- 2025-03-01
- Completion
- 2025-12-01
- First posted
- 2020-06-04
- Last updated
- 2023-07-06
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT04414735. Inclusion in this directory is not an endorsement.