Clinical Trials Directory

Trials / Completed

CompletedNCT04414150

A Trial of SHR-1802 in Patients With Failure of Standard Treatment for Advanced Malignant Tumours

Tolerability, Safety and Pharmacokinetic Characteristics of SHR-1802 in Patients With Advanced Malignancy: a Phase I Clinical Study

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
28 (actual)
Sponsor
Jiangsu HengRui Medicine Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This is the first study to test SHR-1802 in humans. The primary purpose of this study is to see if SHR-1802 is safe and tolerable for patients with locally advanced/unresectable or metastatic malignancies that are refractory to available therapy or for which no standard therapy is available.

Conditions

Interventions

TypeNameDescription
DRUGSHR-1802This study will evaluate the preliminary safety, tolerability, pharmacokinetic characteristics and initial efficacy of SHR-1802 The goal is to establish the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of sequential escalating doses of SHR-1802 when administered to patients with locally advanced/ unresectable or metastatic malignant tumours that are refractory to available therapy or for which no standard therapy is available.

Timeline

Start date
2020-06-17
Primary completion
2022-01-13
Completion
2022-03-15
First posted
2020-06-04
Last updated
2022-10-26

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04414150. Inclusion in this directory is not an endorsement.