NCT04413487

Early Detection of Heart Problems in Cancer Patients Receiving Chemotherapy

Strain Echocardiogram in Early Detection of Left Ventricular Dysfunction in Cancer Patients Receiving Chemotherapy

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: The Guthrie Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Subjects will include patients diagnosed with breast cancer or hematological cancer who are planned for chemotherapy treatment with anthracycline or trastuzumab; and who have one or more risk factors for cardiovascular disease. Subjects will received an extra echocardiogram to determine if heart problems can be detected earlier.

Detailed description

* Patients scheduled for potentially cardiotoxic chemotherapy would receive a baseline echocardiogram as per standard protocol which should be covered by the routine insurance * Follow-up with an extra echocardiogram for research purposes would be performed after 2 cycles of that chemotherapy - supplied by the study * Clinical assessment at 3 to 6 months including repeat echocardiography as per standard care with the research question as whether any differences in strain pattern between pre-chemo and post 2 cycles studies all identify patients who are more likely to have cardiac issues later. * Patients will have standard of care visits at 3 month, 6 month and 12 month and will be evaluated for cardiac status and survival. * Patient records will be reviewed at 5 years to check cardiac status and survival.

Conditions

• Heart Failure

Interventions

Type	Name	Description
OTHER	Extra echocardiogram	Subjects will receive an extra echocardiogram after 2 cycles of chemotherapy

Timeline

• Start date: 2020-03-01
• Primary completion: 2020-05-28
• Completion: 2020-05-28
• First posted: 2020-06-04
• Last updated: 2020-06-04