NCT04412109

Optic Nerve Sheath Diameter Difference Between Different Injection Volume

Effect of Normal Saline Injection Volume on Epidural Pressure and Optic Nerve Sheath Diameter

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Keimyung University Dongsan Medical Center · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Valid method of indirect measurement of intracranial pressure is using optic nerve sheath diameter. Different volume of injection is known to affect the degree of increase of intracranial pressure. This study is desinged to measure the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.

Detailed description

Previous study showed that different volume of injections (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia showed siginifiant increase of optic nerve sheath diameter in group of high volumes. Increase of ICP can result in harmful effect including reduced cerebral flow and oxygen saturation. Also, increase of ICP can cause headache, syncope and transient loss of visual acuity. The proven and valid method of measuring ICP indirectly is using optic nerve sheath diameter. This study was designed to examine the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal saline was injected.

Conditions

• Optic Nerve Sheath Diameter

Interventions

Type	Name	Description
PROCEDURE	thoracic epidural catheterization	thoracic epidural catheterization for postoperative pain control

Timeline

• Start date: 2020-05-25
• Primary completion: 2020-11-16
• Completion: 2020-11-16
• First posted: 2020-06-02
• Last updated: 2020-11-18

Locations

1 site across 1 country: South Korea