NCT04410497

Silver Foam Dressing Superior to Porcine Xenograft in Pediatric Scalds

Silver Foam Dressing Superior to Porcine Xenograft in Pediatric Scalds: A Prospective Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: University Hospital, Linkoeping · Academic / Other
• Sex: All
• Age: 6 Months – 6 Years
• Healthy volunteers: Not accepted

Summary

Prospective randomized trial where two dressings has been compared for partial thickness scald burns in children 6 months to 6 years.

Detailed description

Aim: The aim of this study was to compare two different treatment regimes for children with partial-thickness scald burns. Burns were treated with either a porcine xenograft (EZderm®, Mölnlycke Health Care, Gothenburg, Sweden) or a silver foam dressing (Mepilex® Ag, Mölnlycke Health Care, Gothenburg, Sweden). Methods: A prospective randomized clinical trial including 58 children admitted between May 2015 and May 2018 for partial-thickness scalds to The Burn Centre in Linkoping, Sweden. Primary outcome was time to wound closure. Secondary outcomes were pain, need of surgery, wound infection, length of hospital stay, required dressings changes, and labour time.

Conditions

• Burns Scald

Interventions

Type	Name	Description
OTHER	Porcine xenograft (wound dressings)	commercial porcine xenograft, derived from acellular dermis from porcine.
OTHER	Silver foam (wound dressings)	commercial silver containing foam dressing

Timeline

• Start date: 2015-05-11
• Primary completion: 2018-05-08
• Completion: 2018-05-08
• First posted: 2020-06-01
• Last updated: 2020-06-01

Locations

1 site across 1 country: Sweden