Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04409483

Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger

Status
Withdrawn
Phase
Phase 3
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Epicentre · Academic / Other
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess whether lopinavir/ritonavir (or eventually other antiviral drugs) is effective at reducing the rate of hospitalization among confirmed COVID-19 cases treated as outpatients.

Detailed description

After being informed about the study and potential risks, all patients who meet all eligibility criteria and who give written informed consent will be randomized to receive standard care or standard care plus lopinavir/ritonavir (400mg/100mg twice daily for 14 days). Participants will receive daily visits from study staff for 15 days and be followed for a total of 28 days.

Conditions

Interventions

TypeNameDescription
DRUGLopinavir-Ritonavir Drug Combination400mg/100mg taken orally twice daily for 14 days.
COMBINATION_PRODUCTStandard CareParacetamol as needed for the symptomatic treatment of fever and vitamin C 1000 mg daily

Timeline

Start date
2020-06-01
Primary completion
2020-12-31
Completion
2020-12-31
First posted
2020-06-01
Last updated
2021-02-10

Source: ClinicalTrials.gov record NCT04409483. Inclusion in this directory is not an endorsement.