NCT04408547

Technical Factors of Embryo Transfer Procedure That Might Affect the Outcome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,512 (actual)
• Sponsor: Iakentro Fertility Centre · Academic / Other
• Sex: Female
• Age: 18 Years – 49 Years
• Healthy volunteers: Not accepted

Summary

Analysis our Embryo transfer data, prospectively collected during the last 6 years (2014- 2019), performed by the same operator YP, who has been doing embryo transfers since 1984. All factors that might impact the embryo transfer will be analyzed. We want to see which factors that influence the success rate are not related to the subjectivity of the operator and could be adjusted through different approaches.

Detailed description

Most patients undergoing IVF or ICSI reach a blastocyst embryo transfer but less achieve pregnancy and live birth. Many reasons have been proposed to explain these results. Among them, the factor Embryo Transfer Procedure gained less of the attention since few papers have been published and most of them had a lot of biases. In order to eliminate possible biases, we wanted to analyze our Embryo transfer data, prospectively collected during the last 6 years (2014- 2019), performed by the same operator YP, who has been doing embryo transfers since 1984. All factors that might impact the embryo transfer will be analyzed. We want to see which factors that influence the success rate are not related to the subjectivity of the operator and could be adjusted through different approaches. Primary outcomes: bhCG positive rate, pregnancy rate, ongoing pregnancy rate, live birth rate. Secondary outcomes: Full bladder, uterine ax orientation, Endometrial thickness, type of catheter, straightforward advancement of the preloaded catheter, use of a stiffer hard catheter to pass through the cervix and the orifice, the site of the uterine cavity that the embryo was released, single or double transfer due to blocked embryo in the catheter. In addition for each embryo transfer variables that may influence the pregnancy rates will be collected: age of the woman, number of oocytes harvested, sperm characteristics, fertilization rate, stage and grade of the embryos the day of transfer

Conditions

• IVF
• Pregnancy

Interventions

Type	Name	Description
DEVICE	embryo transfer catheter	undergoing embryo transfer

Timeline

• Start date: 2014-01-03
• Primary completion: 2019-12-30
• Completion: 2019-12-30
• First posted: 2020-05-29
• Last updated: 2020-06-04

Locations

1 site across 1 country: Greece