NCT04407052

Double Trigger in Patients With Low Proportion of Mature Oocytes

Double Trigger in Patients With Low Proportion of Mature Oocytes. A Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 66 (estimated)
• Sponsor: Riyadh Fertility and Reproductive Health center · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the number of mature oocytes in patients with history of low proportion of mature oocytes in previous IVF cycle triggered by HCG.

Conditions

• Infertility, Female

Interventions

Type	Name	Description
DRUG	Double trigger	Final follicular maturation is triggered by the coadministration of GnRH-agonist (Triptorelin acetate, decapeptyl 0.2 mg, Slough, United Kingdom) and 10000 IU of HCG, 40 and 34 h prior to oocyte retrieval, respectively
DRUG	HCG trigger	Final follicular maturation is triggered by a dose of 10000 IU of HCG 36 h prior to oocyte retrieval

Timeline

• Start date: 2020-05-30
• Primary completion: 2020-12-31
• Completion: 2021-02-02
• First posted: 2020-05-29
• Last updated: 2020-05-29

Locations

1 site across 1 country: Egypt