NCT04405128

Brain TV (Tissue Velocimetry) for Emergency Assessment of Suspected Stroke

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 102 (actual)
• Sponsor: University of Leicester · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study uses a Doppler ultrasound technique being developed at the University of Leicester called \"Brain Tissue Velocimetry\" (Brain TV), to investigate brain tissue motion over the cardiac cycle.

Detailed description

Brain motion is highly sensitive to heart and brain biomechanics, but the impact of brain injury on brain tissue motion has yet to be explored. Preliminary brain tissue motion measurements from a small number of patients suggest that brain biomechanics may be disturbed in the presence of brain injury. This study combines transcranial tissue Doppler (TCTD) ultrasound with brain magnetic resonance imaging (MRI) to establish whether analysis of brain tissue motion provides clinically useful information for emergency diagnosis and monitoring of suspected stroke.

Conditions

• Stroke

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Transcranial Tissue Doppler (TCTD)	Doppler ultrasound technique called "Brain Tissue Velocimetry" (Brain TV), to investigate brain tissue motion over the cardiac cycle.
DIAGNOSTIC_TEST	Brain Magnetic Resonance Imaging	Brain MRI for investigation of brain tissue motion in the presence of suspected stroke.

Timeline

• Start date: 2019-08-01
• Primary completion: 2023-01-01
• Completion: 2023-12-31
• First posted: 2020-05-28
• Last updated: 2024-09-20

Locations

1 site across 1 country: United Kingdom