NCT04403997

Virtual Chromoendoscopy With Second Generation NBI (HQ190) vs Chromoendoscopy in Inflammatory Bowel Disease

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 175 (estimated)
• Sponsor: Hospital Universitario La Paz · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Study to compare the detection of neoplastic lesions between chromoendoscopy and NBI

Detailed description

Single-blind (patient) randomized study to compare detection of neoplastic lesions between chromoendoscopy and NBI. Patients with Inflammatory Bowel Disease who are to undergo chromoendoscopy according to usual clinical criteria will be included. The endoscopic procedure is similar to the one usually performed. All patients will undergo colonoscopy according to the usual procedure, with Olympus HQ190 series endoscopes, with the same bowel preparation. During intubation, the faecal remains will be thoroughly washed. Patients will be randomly assigned to one of the two techniques: Chromoendoscopy with 0.1% methylene blue or New generation NBI with Near focus. Biopsies will be taken of all those lesions detected, instead of random biopsies.

Conditions

• Chromoendoscopy

Interventions

Type	Name	Description
PROCEDURE	Chromoendoscopy	Chromoendoscopy is an endoscopic technique used in the follow-up of inflammatory bowel disease of long evolution. Chromoendoscopy, through the application of specific dyes used directly on the intestinal mucosa, promotes the visualization of mucosal lesions.

Timeline

• Start date: 2019-10-01
• Primary completion: 2021-12-30
• Completion: 2022-02-25
• First posted: 2020-05-27
• Last updated: 2021-07-23

Locations

1 site across 1 country: Spain