Trials / Completed
CompletedNCT04403971
0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia
Effect of 0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia Among Hospitalized Patients
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 103 (actual)
- Sponsor
- National Cheng-Kung University Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 100 Years
- Healthy volunteers
- Not accepted
Summary
Chlorhexidine is a effective strategy in reducing ventilator associated pneumonia. However, it is unclear if prophylactic 0.12% chlorhexidine oral rinse can reduce the risk of non-ventilator hospital-acquired pneumonia among hospitalized patients.
Detailed description
Participants will be classified into three groups, applied twice a day by care givers. Oral colonization will be tested in the baseline, day-3, day-7, and at the discharge. Quantitation of colonization of the oral cavity by oral rinses and respiratory pathogens were measured.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | 0.12% Chlorhexidine Oral Liquid Product | The intervention group 1 received 10ml 0.12% chlorhexidine solution for oral rinse twice a day. |
| DRUG | Listerine Oral Liquid Product | The intervention group 2 received 10ml Listerine solution for oral rinse twice a day. |
| OTHER | Normal Saline Product | The control group received 10ml normal saline for oral rinse twice a day. |
Timeline
- Start date
- 2020-05-25
- Primary completion
- 2020-10-31
- Completion
- 2020-12-31
- First posted
- 2020-05-27
- Last updated
- 2021-12-14
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT04403971. Inclusion in this directory is not an endorsement.