NCT04403503

The Influence of Tissue Adhesive to Palatal Donor Site Healing.

The Influence of Tissue Adhesive to Palatal Donor Site Healing. A Randomized Controlled Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: Hacettepe University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

CTG was harvested from 21 patients in each group. Donor site was treated with either GS (control) or GS+CY (test). Palatal tissue thickness, graft dimensions, working time (WT) and primary bleeding time were recorded intraoperatively. The data of pain perception (PP) will be measured using visual analog scale, quantity of analgesics (QA), secondary bleeding (SB), epithelization level (EL), and color match (CM) will be assessed prospectively. these outcomes will be evaluated in the first 7 days and 14th, 21th, and 28th days. Patient reported outcomes will be recorded using OHIB 14 questionnaire.

Conditions

• Donor Site Complication

Interventions

Type	Name	Description
DRUG	Gelatin Sponge;Thrombin, Bovine 5000 IU Multiple Routes Kit [GELFOAM-JMI SPONGE KIT]	Donor site was closed either with GS (Spongostan®, Ethicon, Somerville, USA) (GS group)
DRUG	Cyanoacrylate, Isobutyl	Donor site was closed either with GS (Spongostan®, Ethicon, Somerville, USA) (GS group) and GS covered with high viscosity CY (PeriAcryl®, Glustitch Inc., Delta, Canada) (GS+CY group).

Timeline

• Start date: 2018-07-01
• Primary completion: 2019-02-01
• Completion: 2019-03-01
• First posted: 2020-05-27
• Last updated: 2024-10-02

Locations

1 site across 1 country: Turkey (Türkiye)