Clinical Trials Directory

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UnknownNCT04397588

Extracorporeal Membrane Oxygenation (ECMO) and Coronavirus Disease (COVID) 19

Extracorporeal Membrane Oxygenation (ECMO) as a Therapeutic Option in Severe Form of COVID-19: a Nationwide Cohort Study

Status
Unknown
Phase
Study type
Observational
Enrollment
300 (estimated)
Sponsor
Rennes University Hospital · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The role of ECMO in the treatment of patients with severe COVID-19 (Acute Respiratory Distress Syndrome (ARDS) and/or acute refractory heart failure) is not yet known. The present study will aim to report the results of the ECMO management of the most severe forms of COVID-19 through the first French ECMO registry.

Detailed description

The main objective of this study is to evaluate the hospital survival of COVID-19 patients supported by venovenous or venoarterial ECMO in a multicenter registry. The secondary objectives are to describe the characteristics of COVID-19 patients who have received ECMO support, to identify the risk factors associated with hospital mortality, to analyze the outcomes after ECMO weaning including survival at day 28 and day 90, and to analyze the utility of a circulatory support mobile unit in a severe pandemic Inclusions are both prospective and retrospective in order to collect data over the whole pandemic

Conditions

Timeline

Start date
2020-04-21
Primary completion
2020-10-21
Completion
2020-10-21
First posted
2020-05-21
Last updated
2020-08-31

Locations

44 sites across 1 country: France

Source: ClinicalTrials.gov record NCT04397588. Inclusion in this directory is not an endorsement.