NCT04397341

Biweekly TPF Induction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of Head and Neck

A Phase II Study of Biweekly Induction Regimen With Docetaxel, Cisplatin and Fluorouracil for Patients With Locally Advanced Squamous Cell Carcinoma of Head and Neck

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: China Medical University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to assess the efficacy and safety for biweekly TPF as induction chemotherapy for locally advanced head and neck cancer

Detailed description

After being informed the study and potential risk, patients was provided written informed consent prior to initiating therapy. The chemotherapy regimen including docetaxel, cisplatin, 5-fluorouracil, and leucovorin was administered every 14 days for six cycles or until disease progression or intolerant treatment toxicity.

Conditions

• Locally Advanced Head and Neck Carcinoma

Interventions

Type	Name	Description
DRUG	docetaxel, cisplatin, fluorouracil	Biweekly Induction regimen with Docetaxel, Cisplatin and Fluorouracil

Timeline

• Start date: 2014-03-01
• Primary completion: 2016-08-30
• Completion: 2019-09-15
• First posted: 2020-05-21
• Last updated: 2020-05-21