NCT04394065

uEXPLORER Total-body PET/CT in Nasopharyngeal Carcinoma

Potential of uEXPLORER Total-body PET/CT in Nasopharyngeal Carcinoma: The Dynamic Imaging, Kinetic Parameters, and Comparison With Conventional PET/CT

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 56 (actual)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: —

Summary

uEXPLORER total-body PET/CT in Nasopharyngeal Carcinoma

Detailed description

A 194-cm-long total-body positron emission tomography/computed tomography (PET/CT) scanner (uEXPLORER), has been constructed to offer a transformative platform for human radiotracer imaging in clinical research and healthcare. The objective of this study is to determine its specific effect in newly diagnosed nasopharyngeal carcinoma compared with conventional PET/CT and the quantitative kinetic parameters including glucose metabolic rate (Ki), glucose transport rate of flow-in (k1) and flow-out (k2) between tissue and blood, and glucosamine-6-phosphatization rate in tissue (k3). All the neck lymph nodes suspected for metastatic in PET/CT were biopsied under the guidance of ultrasound for a pathological diagnosis.

Conditions

• Nasopharyngeal Carcinoma

Interventions

Type	Name	Description
DEVICE	ultrasensitive positron emission tomography	A 194-cm-long total-body positron emission tomography/computed tomography (PET/CT) scanner (uEXPLORER)

Timeline

• Start date: 2020-06-20
• Primary completion: 2021-02-20
• Completion: 2021-06-20
• First posted: 2020-05-19
• Last updated: 2021-09-17

Locations

1 site across 1 country: China

Regulatory

• FDA-regulated device study