NCT04389463

Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic

Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic ; International Cohort Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 350 (estimated)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

This study will describe the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will focus on hemodynamic failure and organ dysfunction after surgery. Capturing real-world data and sharing international experience will inform the management of this complex group of patients who undergo surgery throughout the COVID-19 pandemic, improving their clinical care. This investigator-led, non-commercial, non-interventional does not collect any patient identifiable information.

Detailed description

Performing cardiac surgery in the context of SARS-CoV2 infection is potentially at risk of marked post-operative hemodynamic failure (shock) due to the inflammatory reaction generated by the surgery and the extracorporeal circulation associated with the viral infection. In addition, in the absence of infection, 30-50% of patients will experience acute post-operative respiratory failure due to the combined effects of extracorporeal circulation and general anesthesia. The pulmonary tropism of the virus therefore is susceptible to increase in post-operative respiratory impairment. Thus, the infection is likely to favor the occurrence of post-operative shock but also to aggravate respiratory failure and other post-operative organ failures. Therefore, the investigators designed an observational study that aims at comparing two groups of patients: * Cardiac or thoracic surgery patients with a negative Covid-19 PCR pre-operatively and in the 15 following days * Cardiac or thoracic surgery patients with a positive Covid-19 PCR in the 15 days before surgery

Conditions

• Patients Undergoing Cardiac or Thoracic Surgery

Interventions

Type	Name	Description
OTHER	No intervention	No description

Timeline

• Start date: 2020-05-11
• Primary completion: 2026-05-11
• Completion: 2026-06-30
• First posted: 2020-05-15
• Last updated: 2025-09-08

Locations

1 site across 1 country: France