NCT04389424

Relationship Between Body Composition, Food Consumption, and Micro and Macronutrients With Gene Expression in Breast Cancer

Evaluation of the Relationship Between Drug Therapy, Food Consumption, Body Composition and Plasma Micronutients Levels With the Expression of Genes Related to Metabolism, Aging and Immunity in Women With Breast Cancer.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Instituto Jalisciense de Cancerologia · Other Government
• Sex: Female
• Age: 18 Years – 98 Years
• Healthy volunteers: Not accepted

Summary

The protocol involves measurement of 25 hidroxy vitamin D, gene expression of cytochrome and vitamin D receptor , endoxifen, tamoxifen, exemestane, and other metobolites related to nutrition and endocrine metabolism.

Conditions

• Breast Cancer
• Endocrine Therapy
• Endocrine Therapy Adverse Reaction
• Vitamin D Deficiency
• Nutrition Disorders
• Obesity

Interventions

Type	Name	Description
DRUG	Tamoxifen	Use of tamoxifen for breast cancer recurrence prevention
DRUG	Exemestane	Use of exemestane for breast cancer recurrence prevention
DRUG	Anastrozole	Use of anastrozole for breast cancer recurrence prevention
DIAGNOSTIC_TEST	Basal	Initial diagnosis of breast cacner by biopsy or mastectomy
DIAGNOSTIC_TEST	Recurrence	Breast cancer recurrence under endocrine therapy

Timeline

• Start date: 2017-09-01
• Primary completion: 2020-05-15
• Completion: 2022-01-30
• First posted: 2020-05-15
• Last updated: 2020-05-15

Locations

1 site across 1 country: Mexico