Trials / Unknown
UnknownNCT04389346
A Cone Beam Computed Tomographic Evaluation of Healing of Apicomarginal Defects Using Autologous Platelet Aggregates
A Cone Beam Computed Tomographic Evaluation of Healing of Apicomarginal Defects Using Autologous Platelet Aggregates : A Randomized Controlled Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This study will evaluate the effect of PRF (platelet rich fibrin) on the healing of apicomarginal defects. Healing of the defects will be assessed 2 dimensionaly by periapical radiograph and 3 dimensionaly using CBCT.
Detailed description
Patients with apicomarginal defects as per the inclusion criteria will be randomly divided into two groups - (1) Test group - The denuded root surface will be covered by PRF (Choukron's method) and (2) Control group -No use of autologous platelet aggregate during periapical surgery. Radiographic and clinical healing will be assessed after 12 months, 2D healing will be assessed by Rud and Molven criteria and 3D healing will be assessed by Modified Penn 3D criteria.The clinical parameters recorded including periodontal pocket depth (PD), clinical attachment level (CAL) and gingival margin position (GMP) will be measured on buccal aspect of the interproximal space and mid buccal aspect of the involved teeth using Williams 'O' periodontal probe.Routine examination procedure will be used to evaluate any evidence of signs and/or symptoms.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Periapical surgery using autologous platelet aggregate | PRF will be placed over the denuded root surface, following apicoectomy and before flap repositioning |
| PROCEDURE | Periapical surgery without autologous platelet aggregate | Flap will be repositioned following apicoectomy directly without placing any platelet aggregate |
Timeline
- Start date
- 2019-07-01
- Primary completion
- 2021-03-01
- Completion
- 2021-03-01
- First posted
- 2020-05-15
- Last updated
- 2020-05-19
Locations
1 site across 1 country: India
Source: ClinicalTrials.gov record NCT04389346. Inclusion in this directory is not an endorsement.