NCT04387838

Study of the SARS-COV-2 (COVID-19) Serological Profile of an Army Training Hospital Staff

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 845 (actual)
• Sponsor: Direction Centrale du Service de Santé des Armées · Academic / Other
• Sex: All
• Age: 18 Years – 62 Years
• Healthy volunteers: Accepted

Summary

Emerging in China in December 2019, Covid-19, whose pathogen is SARS-Cov-2, was declared a global pandemic in March 2020. The clinical presentation is highly variable, ranging from asymptomatic forms to acute respiratory distress and even death. Transmission occurs through droplets, with a R0 of approximately 3. Rapidly, population protection measures were put in place by governments, including the confinement of all persons whose functions were not considered essential and the closure of educational institutions. Health care institutions are places at risk of Covid-19 transmission and hospital staff are particularly exposed, either through direct contact with patients, contact with exposed persons or through the environment. In order to protect personnel, hygiene measures were immediately recalled and reinforced. This study is aimed at evaluating the incidence rate of anti-SARS-Cov2 seroconversion over 2 months among hospital staff, without any supposed anti-Covid treatment 19.

Conditions

• Sars-CoV2

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Anti-SARS-CoV2 Serology	A blood sample is collected by venipuncture at Day 0, Day 30 and Day 60. The anti-SARS-CoV2 serological status is measured by automated microplate ELISA technique on the EVOLIS analyzer (Biorad®), using reagent kits from EUROIMMUN France.
OTHER	Questionnaire	Data concerning personal exposure factors are collected in a questionnaire: * Socio-demographic factors: sex, age * Professional factors: Employment (type, pace, reception, service, care practices), wearing of personal protective equipment (type of equipment, frequency of use) and type of hospital * Non-professional factors: Contact with infected individuals, carrying of professional equipment and compliance with barrier measures

Timeline

• Start date: 2020-05-14
• Primary completion: 2020-08-15
• Completion: 2020-08-15
• First posted: 2020-05-14
• Last updated: 2021-03-09

Locations

2 sites across 1 country: France