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Trials / Not Yet Recruiting

Not Yet RecruitingNCT04384601

Dragon III-Phase 3: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer

Efficacy Study of FLOT Versus SOX Regimen as Neoadjuvant Chemotherapy for Patients With Locally Advanced Gastric Cancer: A Phase 3 Multi-center Randomized Controlled Trial

Status
Not Yet Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
246 (estimated)
Sponsor
Ruijin Hospital · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

DRAGON III research, Neoadjuvant Chemotherapy (FLOT versus SOX) for Gastric Cancer, is an investigator initiated; phase 3, open label, multi-center randomized controlled study.

Detailed description

Non inferiority of SOX will be tested against FLOT. This study will be conducted at multiple center of China and will invite international centers to join it.The sponsor of this study is Ruijin Hospital and the project is supported by the Shanghai Key Laboratory of Gastric Neoplasms and Institute of Digestive Surgery, Shanghai.

Conditions

Interventions

TypeNameDescription
DRUGChemotherapyPerioperative chemotherapy will be administered according to description in two arms.

Timeline

Start date
2021-09-01
Primary completion
2022-09-01
Completion
2027-09-01
First posted
2020-05-12
Last updated
2021-07-19

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04384601. Inclusion in this directory is not an endorsement.