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UnknownNCT04383353

Pan-canceR Early DetectIon projeCT

Burning Rock Pan-canceR Early DetectIon projeCT (PREDICT): a Prospective, Multicenter Study to Develop and Validate the Performance of a cfDNA Methylation Based Model on Early Cancer Detection

Status
Unknown
Phase
Study type
Observational
Enrollment
14,026 (estimated)
Sponsor
Guangzhou Burning Rock Dx Co., Ltd. · Industry
Sex
All
Age
40 Years – 75 Years
Healthy volunteers
Accepted

Summary

PREDICT is a prospective, multi-center study for the early detection of pan-cancer through cell-free DNA (cfDNA) methylation based model, in which approximately 14,000 participants will be enrolled. The development and validation of the model will be conducted in participants with early stage cancers or benign diseases, along with non-tumor (healthy) individuals through a two-stage approach. The sensitivity and specificity of the model in cancer early detection will be evaluated, and the accuracy of the identification for tissue of origin will be obtained.

Conditions

Timeline

Start date
2020-07-21
Primary completion
2022-10-01
Completion
2023-03-01
First posted
2020-05-12
Last updated
2020-07-22

Locations

3 sites across 1 country: China

Source: ClinicalTrials.gov record NCT04383353. Inclusion in this directory is not an endorsement.