NCT04382989

Factors Influencing the Composition of Human Milk

The Influence of Various Maternal, Infant and Environmental Factors on Human Milk Composition Among Lithuanian Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 174 (actual)
• Sponsor: Vilnius University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

This study aims for characterization of different maternal, infant and environmental factors (e.g. maternal age, pregnancy duration, lactation period, baby gender, circadian rhythm, Holder pasteurisation, etc.) that influence human milk composition.

Detailed description

The study consists of three parts. In the first part the investigators aim to evaluate human milk macronutrient composition depending on the time after delivery and pregnancy duration. In the second part the investigators aim to evaluate the circadian variation of human milk macronutrient and energy content depending on pregnancy duration. In the third part the investigators aim to evaluate the influence of Holder pasteurisation on human milk macronutrient, metabolome and bioactive protein (lysozyme and lactoferrin) content.

Conditions

• Breast Milk Collection

Interventions

Type	Name	Description
DEVICE	Analysis of human milk composition by mid-infrared spectrophotometry	Analysis of human milk macronutrient content was performed by mid-infrared spectrophotometry using a Miris Human Milk Analyser. An immune-enzymatic ELISA assays were used to estimate lysozyme and lactoferrin concentrations in human milk.

Timeline

• Start date: 2017-09-15
• Primary completion: 2020-04-30
• Completion: 2020-04-30
• First posted: 2020-05-11
• Last updated: 2020-06-04

Locations

1 site across 1 country: Lithuania