Clinical Trials Directory

Trials / Terminated

TerminatedNCT04381988

A Study of Hydroxychloroquine vs Placebo to Prevent COVID-19 Infection in Patients Receiving Radiotherapy

A Phase II Randomized Double-Blind Placebo-Controlled Clinical Trial Of Hydroxychloroquine For Prophylaxis Against Covid-19 In Patients Receiving Radiotherapy (COVID)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
4 (actual)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The researchers are doing this study to find out whether the study drug hydroxychloroquine can prevent infection with the COVID-19 virus, compared with placebo, in people who are receiving radiation therapy for their cancer. The placebo used in this study is a tablet that looks the same as the study drug and is taken in the same way, but it does not contain any active ingredients.

Conditions

Interventions

TypeNameDescription
DRUGHydroxychloroquine400mg daily
OTHERPlacebo400mg daily
RADIATIONRadiation therapyStandard radiation therapy will be prescribed and administered as per the patient's radiation oncologist.

Timeline

Start date
2020-05-07
Primary completion
2021-04-21
Completion
2021-04-21
First posted
2020-05-11
Last updated
2021-10-27
Results posted
2021-10-27

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04381988. Inclusion in this directory is not an endorsement.