Clinical Trials Directory

Trials / Terminated

TerminatedNCT04381494

Mobile Devices to Detect Early Pneumonitis in Stage III NSCLC Patients on Durvalumab.

Prospective, Interventional Pilot Study of Mobile Devices and Digital Applications to Detect Early Pneumonitis and Other Pulmonary Adverse Events in Unresectable Stage III Non-Small Cell Lung Cancer Patients on Durvalumab

Status
Terminated
Phase
Phase 4
Study type
Interventional
Enrollment
40 (actual)
Sponsor
AstraZeneca · Industry
Sex
All
Age
18 Years – 130 Years
Healthy volunteers
Not accepted

Summary

A study of whether mobile devices can improve the detection of pulmonary AEs (including pneumonitis) in stage III NSCLC patients post-CRT, while on durvalumab.

Detailed description

Patients undergoing post-CRT treatment for lung cancer with consolidation durvalumab can experience pulmonary AEs that could become severe if not recognized and treated in time. Data collected will be used to evaluate the likelihood of early detection of pulmonary AEs in unresectable Stage III NSCLC patients on durvalumab. This project seeks to understand if multiparametric mobile technology collecting patient reported outcomes, vital signs, and respiratory function, integrate well into a patients daily life and aid physicians in early detection of pulmonary AEs.

Conditions

Interventions

TypeNameDescription
DEVICEMultiparametric Mobile TechnologyUsing a spirometer, an armband, and a tablet to collect data.

Timeline

Start date
2020-04-27
Primary completion
2022-01-27
Completion
2022-01-27
First posted
2020-05-08
Last updated
2023-06-22
Results posted
2023-06-22

Locations

18 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04381494. Inclusion in this directory is not an endorsement.