NCT04377854

Prognostic Value of BNP in MCS - a 25 Year Follow up Study

The Prognostic Value of proBNP in Patients Supported With Durable Mechanical Circulatory Assist Devices - a 25 Year Follow up Study.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

A biobank has been created to investigate the prognostic value of biomarkers (mainly BNP) in patients implanted with durable mechanical assist devices comparing patients with advanced HF supported by MCS with those who are transplanted and those who remain on optimal medical therapy. Patients will be followed up for 25 years after inclusion.

Detailed description

All patients referred for advanced HF treatment at the Dept of Cardiology at Rigshospitalet.

Conditions

• Heart Failure
• Left Ventricular Assist Device
• Prognosis
• Durable Mechanical Support Device

Interventions

Type	Name	Description
OTHER	Observation. No intervention per se.	Observation. No intervention (no collection of blood).
OTHER	2) Observation and collection and of blood sample	All patients evaluated for adv HF (HTX/LVAD) will be offered to contribute to this database; Blood samples will be collected from all at baseline. Patients receiving LVAD will contribute on a yearly basis (or until withdrawal of consent). For other patients no further blood will be collected unless they receive an LVAD at a later point.

Timeline

• Start date: 2020-09-18
• Primary completion: 2045-08-01
• Completion: 2045-08-01
• First posted: 2020-05-06
• Last updated: 2021-05-05

Locations

1 site across 1 country: Denmark