NCT04377321

Colchicine Has Anti-diabetic Effect

Colchicine Has Anti-diabetic Effect and May be an Option for Type 2 Diabetes Management

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 150 (actual)
• Sponsor: Ministry of Health and Population, Egypt · Other Government
• Sex: All
• Age: 35 Years – 55 Years
• Healthy volunteers: —

Summary

Colchicine has antidiabetic effect and may be an option for type 2 diabetes management

Detailed description

Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years. The aim of this study was to evaluate colchicine effect on A1C of newly diagnosed type2 diabetes compared to the metformin and control group on diet only. The first group patients received colchicine 0.5twice daily for 6 months, the second group received metformin 1gm twice daily, the third group patients were on diet only. During the period of treatment, the investigators followed the patients if there were side effects of the drugs used. No side effects were monitored during the period of treatment except for gastric upset in some patients using metformin

Conditions

• Treatment Adherence

Interventions

Type	Name	Description
DRUG	Colchicine Tablets	colchicine tabletes for 6 months

Timeline

• Start date: 2019-10-10
• Primary completion: 2020-05-01
• Completion: 2020-05-02
• First posted: 2020-05-06
• Last updated: 2020-05-06

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study