Clinical Trials Directory

Trials / Unknown

UnknownNCT04377243

Immunotherapy of Chronic Kidney Failure

Phase II Trial of V8 in Treating Kidney Failure

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
20 (estimated)
Sponsor
Immunitor LLC · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

Kidney failure can result from inflammatory renal disease in the context of autoimmunity because the kidney is targeted by host's immune response against self. There are many causes to this, but abnormal kidney function tests, i.e., BUN and creatinine, can reveal the disease. Oral delivery of kidney cells is ought to produce the immune tolerance - phenomenon is known as oral tolerance. Preliminary studies produced convincing evidence that this hypothesis holds true and has not produced any adverse side effects. Intended open label Phase II aims to confirm these findings.

Conditions

Interventions

TypeNameDescription
BIOLOGICALV8one pill per day either V8 or placebo

Timeline

Start date
2020-06-16
Primary completion
2021-05-15
Completion
2021-09-01
First posted
2020-05-06
Last updated
2020-05-08

Locations

1 site across 1 country: Mongolia

Source: ClinicalTrials.gov record NCT04377243. Inclusion in this directory is not an endorsement.