Trials / Unknown
UnknownNCT04374214
Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars
Effect of Simvastatin on Success of Pulpotomy in Cariously Exposed Permanent Molars: a Randomized Control Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 56 (estimated)
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak · Academic / Other
- Sex
- All
- Age
- 15 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The study will compare the outcome of complete pulpotomy in mature permanent mandibular molars with deep carious lesions by using Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate as medicament agent
Detailed description
After a thorough history, clinical and radiographic examination with all eligibility confirmation, written informed consent will be taken from the patient after explaining the procedure, its associated risks and benefits. Clinical diagnosis of reversible pulpitis will be established. Complete pulpotomy will be done in both groups. Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate will be used as pulpotomy agents. Pain analysis will be carried out preoperatively and postoperatively at every 6 hours for 1 day and then every 24 hours till 7 days after the intervention. All the subjects will be followed up for evaluation of clinical and radiographic success at 3, 6 months and 1 year.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Complete Pulpotomy using Mineral Trioxide Aggregate | Inflammed coronal pulp tissue will be removed till the canal orifices and mineral trioxide aggregate placed over the amputated pulp stump. |
| PROCEDURE | Complete Pulpotomy using Simvastain -alphatricalcium phosphate | Inflammed coronal pulp tissue will be removed till the canal orifices and Simvastatin -alpha tricalcium phosphate placed over the amputated pulp stump. |
Timeline
- Start date
- 2018-12-01
- Primary completion
- 2020-04-30
- Completion
- 2020-06-30
- First posted
- 2020-05-05
- Last updated
- 2020-05-05
Locations
1 site across 1 country: India
Source: ClinicalTrials.gov record NCT04374214. Inclusion in this directory is not an endorsement.