NCT04373226

Arithmetic Abilities in Children With 22q11.2DS

Study of Arithmetic Abilities of Children With 22q11.2 Deletion Syndrome Aged From 4 to 11 Years Old

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Hôpital le Vinatier · Academic / Other
• Sex: All
• Age: 4 Years – 11 Years
• Healthy volunteers: Accepted

Summary

The study ARITH22 will investigate the role of visuo-spatial attention on arithmetic abilities of children with 22q11.2 deletion syndrome.

Detailed description

Children with 22q11.2 deletion syndrome often have arithmetic learning disability because of magnitude representation impairment. Previous works suggested that magnitude representation impairment could be a result of endogenous visuo-spatial attention dysfunction in 22q11.2DS. Nevertheless this relationship is still poor explored. The influence of visuo-spatial abilities on arithmetic achievement could also be modulated by developmental age. The study ARITH22 will test these hypotheses thanks to magnitude comparisons tasks, in children with 22q11.2 deletion syndrome and matched children without developmental disease.

Conditions

• 22q11.2 Deletion Syndrome

Interventions

Type	Name	Description
BEHAVIORAL	Magnitude comparison tasks and neuropsychological testing	neuropsychological testing (ZAREKI-R) and magnitude comparison tasks with stimuli of different types (visual, visuo-spatial)

Timeline

• Start date: 2020-09-16
• Primary completion: 2023-04-14
• Completion: 2023-04-14
• First posted: 2020-05-04
• Last updated: 2025-03-07

Locations

1 site across 1 country: France