Clinical Trials Directory

Trials / Unknown

UnknownNCT04373018

Evaluation of Three Irrigants, Sodium Hypochlorite, Chlorhexidine and Combination of CHX+H2O2 in Endodontic Treatment.

Comparative Evaluation of Clinical and Radiographic Outcome by Using Three Different Irrigants, Sodium Hypochlorite (NaOCl), Chlorhexidine (CHX) and Combination of CHX+H2O2 in Primary Endodontic Treatment

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
90 (estimated)
Sponsor
Postgraduate Institute of Dental Sciences Rohtak · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

This study will evaluate the synergistic effect of CHX + H2O2 when used as an irrigant during biomechanical preparation.in root canal treatment on periapical healing and compared with Chlorhexidine( CHX) and Sodium Hypochlorite (NaOCl).

Detailed description

After a thorough history, clinical and radiographic examination with all eligibility confirmation, written informed consent will be taken from the patient after explaining the procedure and its associated risks and benefits. Patients randomly allocated to one of the three study groups Sodium hypochlorite (NaOCl), Chlorhexidine (CHX) and combination of (CHX+H2O2). All three irrigants will be used according to standard protocol during biomechanical preparation. Pain analysis will be carried out preoperatively and postoperatively at every 6 hours for 1 day and then every 24 hours till 7 days after the intervention. All the subjects will be followed up for evaluation of clinical and radiographic success at 3, 6 months and 1year.

Conditions

Interventions

TypeNameDescription
PROCEDURESodium hypochloriteSodium hypochlorite irrigant will be used during biomechanical preparation.
PROCEDUREChlorhexidineChlorhexidine irrigant will be used during biomechanical preparation.
PROCEDUREChlorhexidine + Hydrogen peroxideChlorhexidine + Hydrogen peroxide irrigant will be used during biomechanical preparation.

Timeline

Start date
2019-12-01
Primary completion
2021-04-01
Completion
2021-04-01
First posted
2020-05-04
Last updated
2020-05-04

Locations

1 site across 1 country: India

Source: ClinicalTrials.gov record NCT04373018. Inclusion in this directory is not an endorsement.