Clinical Trials Directory

Trials / Terminated

TerminatedNCT04372017

Hydroxychloroquine as Post-Exposure Prophylaxis Against COVID-19 Infection

Randomized, Double-Blind, Controlled Trial of Hydroxychloroquine vs Placebo as Post-Exposure Prophylaxis Against COVID-19 Infection

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
1 (actual)
Sponsor
Sanford Health · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

This is a prospective, double-blind, randomized, placebo-controlled study in two distinct cohorts to evaluate the efficacy and safety of hydroxychloroquine in the prevention of COVID-19 infection.

Conditions

Interventions

TypeNameDescription
DRUGHydroxychloroquineParticipants randomized to hydroxychloroquine will take 800mg on day 1 followed by 400mg on days 2-5.
DIETARY_SUPPLEMENTVitamin DParticipants randomized to placebo will take IU1600 on day 1 and IU 800 on days 2-5.

Timeline

Start date
2020-05-14
Primary completion
2021-06-04
Completion
2021-06-04
First posted
2020-05-01
Last updated
2021-12-10
Results posted
2021-12-10

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04372017. Inclusion in this directory is not an endorsement.