NCT04371588

Perioperative Muscle Relaxant and Postoperative Outcomes

Effect of Perioperative Muscle Relaxant Model on Postoperative Outcomes in Chinese Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 999 (actual)
• Sponsor: Air Force Military Medical University, China · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Muscle relaxant is usually needed for surgery. However, the optimal depth of neuro-muscular blockade is still on debate. Deep neuro-muscular blockade may benefit the patients during surgery, but may increase the risk of residual blockade after surgery. Residual blockade has been reported to increase risk of morbidity. In this study, we tend to observe the postoperative outcomes in patients undergoing abdominal surgery under general anesthesia. And to compare the outcomes in patients received different depth of neuro-muscular blockade.

Conditions

• Postoperative Complications

Interventions

Type	Name	Description
OTHER	No Response to Train of Four Stimulation	No response is observed during Train of Four stimulation monitoring during surgery
OTHER	1-2 Response to Train of Four Stimulation	1 to 2 response is observed during Train of Four stimulation monitoring during surgery

Timeline

• Start date: 2018-03-17
• Primary completion: 2021-08-12
• Completion: 2021-08-12
• First posted: 2020-05-01
• Last updated: 2022-09-02

Locations

9 sites across 1 country: China