Clinical Trials Directory

Trials / Completed

CompletedNCT04370028

Study on Efficacy and Safety of Divaza in Patients With Chronic Cerebral Ischemia and Cognitive Disorders

All-Russian Observational Non-interventional Study on Efficacy and Safety of Divaza in Patients With Chronic Cerebral Ischemia and Cognitive Disorders

Status
Completed
Phase
Study type
Observational
Enrollment
2,583 (actual)
Sponsor
Materia Medica Holding · Industry
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

An open-label, prospective, observational, multicenter study. The study enrolls adult outpatients with CCI from 8 federal districts of the Russian Federation.

Detailed description

Medical data (demographic and clinical characteristics - diagnosis, MoCA test results) are collected from patients to whom Divaza is prescribed to be taken according to the following regimen: 2 tablets 3 times per day for 12 weeks. Neurologists assess the patients' cognitive functions with MoCA scale before starting therapy with Divaza (visit 1) and 12 weeks after the treatment (visit 2). The efficacy of Divaza for the treatment of cognitive impairment in patients with chronic cerebral ischemia (CCI) is evaluated. Safety is assessed based on the frequency and severity of adverse events. In addition, the relationship between MoCA test performance and gender or regional social and economic factors is evaluated.

Conditions

Interventions

TypeNameDescription
DRUGDivazaOral administration.

Timeline

Start date
2016-10-01
Primary completion
2017-01-01
Completion
2017-01-01
First posted
2020-04-30
Last updated
2021-03-10
Results posted
2021-03-10

Source: ClinicalTrials.gov record NCT04370028. Inclusion in this directory is not an endorsement.