Trials / Completed
CompletedNCT04369586
A Phase I Clinical Trial of Meplazumab in Healthy Volunteer
A Single Center, Double-blinded, ,Placebo-controlled Phase I Clinical Trial in Healthy Volunteer to Evaluate Tolerance and Pharmacokinetics of Meplazumab of Injection
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 59 (actual)
- Sponsor
- Xijing Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
This is a single center, double-blinded, placebo-controlled phase I clinical trail in healthy volunteer of meplazumab for injection. The primary objective of this phase I trial is to evaluate the safety, tolerability, pharmacokinetic characteristics and occupancy characteristics of peripheral blood cell receptors of meplazumab in healthy volunteer, and provide a reference for the dosage of meplazumab in phase II clinical trial.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | meplazumab for injection | single dose: 6 dose level, multiple dose: 0.3mg/kg/dose |
| DRUG | Placebo | placebo |
Timeline
- Start date
- 2020-04-25
- Primary completion
- 2020-08-18
- Completion
- 2020-11-20
- First posted
- 2020-04-30
- Last updated
- 2021-04-09
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04369586. Inclusion in this directory is not an endorsement.