Trials / Completed
CompletedNCT04368650
RhBMP-2 in Intrabony Defects - A Randomized Controlled Trial
Evaluation of Rhbmp-2 And Sticky Bone in Intrabony Defects - A Randomized Controlled Trial
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- SVS Institute of Dental Sciences · Academic / Other
- Sex
- All
- Age
- 20 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
This study evaluated the regenerative potential of rhBMP-2 gel in intrabony defects when compared to sticky bone (control).
Detailed description
It was done in 40 subjects who were evaluated for a period of 6 months. the results were evaluated clinically (CAL, PPD) and radiographically (bone fill) and after 6 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | BMP-2 | lyophilized Human Bone Morphogenetic Protein-2 was used as an active drug. |
| PROCEDURE | PRF | For the preparation of sticky bone, the patient's venous blood is collected and centrifuged at 2400rpm for 2min which leads to two different layers in the vacutainer the upper autologous fibrin glue (AFG) and the lower RBC portion, the upper AFG is mixed with a particulate bone graft (hydroxyapatite). Within 5-10 min fibrin meshwork was formed |
Timeline
- Start date
- 2017-12-05
- Primary completion
- 2019-09-20
- Completion
- 2019-10-11
- First posted
- 2020-04-30
- Last updated
- 2020-04-30
Locations
1 site across 1 country: India
Source: ClinicalTrials.gov record NCT04368650. Inclusion in this directory is not an endorsement.