Trials / Completed
CompletedNCT04364022
Efficacy of Pragmatic Same-day COVID-19 Ring Prophylaxis for Adult Individuals Exposed to SARS-CoV-2 in Switzerland
Efficacy of Pragmatic Same-day Ring COVID-19 Prophylaxis for Adult Individuals Exposed to SARS-CoV-2 in Switzerland: an Open-label Cluster Randomized Trial
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 326 (actual)
- Sponsor
- Calmy Alexandra · Academic / Other
- Sex
- All
- Age
- 16 Years
- Healthy volunteers
- Accepted
Summary
A study to assess, in a two-arm open-label cluster randomized clinical trial, the efficacy of a 5-day course of LPV/r treatment in preventing COVID-19 in asymptomatic individuals exposed to a SARS-CoV-2 documented index patient, compared to surveillance alone.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Lopinavir/ritonavir | 2x 200mg/50mg, twice daily for 5 days (bid, PO) |
Timeline
- Start date
- 2020-04-23
- Primary completion
- 2021-03-24
- Completion
- 2021-03-24
- First posted
- 2020-04-27
- Last updated
- 2021-04-12
Locations
4 sites across 2 countries: Brazil, Switzerland
Source: ClinicalTrials.gov record NCT04364022. Inclusion in this directory is not an endorsement.