NCT04363112

Association Between a Biological Pattern of Dysregulation of the HPA Axis and Mental Disorders in Children Exposed to Early Life Stress

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: University Hospital, Brest · Academic / Other
• Sex: All
• Age: 8 Years – 10 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to demonstrate an association between a biological pattern of dysregulation of the HPA axis and mental disorders in children exposed to early life stress.

Detailed description

The purpose of this study is to demonstrate an association between a biological pattern of dysregulation of the HPA axis and mental disorders in children exposed to early life stress. Cortisol secretion lead to define two groups : pathologic versus normal cortisol secretion. Mental disorders is evaluate with Mini-Kids II (a mental health questionary) and lead to define two groups : mental disorders versus no mental disorders

Conditions

• Mental Disorder, Child

Interventions

Type	Name	Description
BEHAVIORAL	Mini Kid II	Mini Kid II (Mini International Neuropsychiatric Interview ) is a standardised, hetero mental health questionary for children, according to DSM IV. Mini Kid II will be administered to children between day 3 and 7 during the study.

Timeline

• Start date: 2022-03-28
• Primary completion: 2024-03-04
• Completion: 2024-03-04
• First posted: 2020-04-27
• Last updated: 2024-03-21

Locations

1 site across 1 country: France