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No Longer AvailableNCT04363034

Arkansas Expanded Access COVID-19 Convalescent Plasma Treatment Program

Status
No Longer Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
University of Arkansas · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers

Summary

This is an expanded access treatment protocol to treat up to 100 patients with severe or life-threatening, laboratory confirmed COVID-19 with COVID-19 convalescent plasma.

Detailed description

This is an expanded access treatment protocol to treat up to 100 subjects with severe or life-threatening, laboratory confirmed COVID-19 with COVID-19 convalescent plasma. Subjects will receive 1-2 units (200-400 mL per unit, not to exceed 550 mL total) of ABO compatible, low isohemagglutinin titer, COVID-19 convalescent plasma. Plasma will be administered one unit per day for up to two days. The duration of infusion will usually take 1 to 2 hours (rate of 100 to 250 mL/hr). The infusion should not exceed 4 hours. Plasma infusions will be administered following standard institutional procedures, including the use of premedications (e.g. acetaminophen, diphenhydramine, etc.) as necessary.

Conditions

Interventions

TypeNameDescription
BIOLOGICALConvalescent Plasma1-2 units (200-400 mL per unit, not to exceed 550 mL total) of ABO compatible, low isohemagglutinin titer, COVID-19 convalescent plasma

Timeline

First posted
2020-04-27
Last updated
2023-03-03

Source: ClinicalTrials.gov record NCT04363034. Inclusion in this directory is not an endorsement.