NCT04362384

Topical Vitamin E Ovules for the Treatment of Hemorrhoids

Topical Endorectal Vietamin E Ovules for the Treatment of Grade 2 and 3 Hemorrhoids

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Hospital General Universitario Elche · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Patients with hemorrohoids grade II and III were included. Patients were randomized into 2 groups: * Experimental group: Patients will receive a treatment with vitamin E ovules, which must be placed inside the annus * Control group: Patients will receive a treatment with corticoid ointment, with endoanal application Bleeding, pain and stinging will be evaluated 14 days after beginning the treatment.

Detailed description

Patients with hemorrohoids grade II and III were included. Patients were randomized into 2 groups: * Experimental group: Patients will receive a treatment with vitamin E ovules, which must be placed inside the annus. 1 ovule must be inserted daily during 14 days. * Control group: Patients will receive a treatment with prednisolone ointment, with endoanal application 3 times per day during 14 days. Bleeding, pain and stinging will be evaluated 14 days after beginning the treatment. Quantification of pain will be performed following a visual analogic scale ranging from 0 (absence of symptoms) to 100 (unbearable symptoms).

Conditions

• Bleeding Anal
• Pain
• Stings

Interventions

Type	Name	Description
DRUG	Vitamin E ovules	Endoanal vitamin E ovules will be prescribed
DRUG	Prednisolone ointment	Endoanal Prednisolone ointment will be prescribed

Timeline

• Start date: 2020-05-01
• Primary completion: 2020-10-30
• Completion: 2020-10-30
• First posted: 2020-04-24
• Last updated: 2020-04-24