Trials / Completed
CompletedNCT04360980
The Effects of Standard Protocol With or Without Colchicine in Covid-19 Infection
Effects of Standard Protocol Therapy With or Without Colchicine in Covid-19 Infection: A Randomized Double Blind Clinical Trial
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 80 (actual)
- Sponsor
- Shahid Beheshti University of Medical Sciences · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Based on data regarding the effect of colchicine on the modulation of immune system and decreasing cytokine release and inflammation the question arises whether colchicine, administered in a relatively low dose, could potentially have an effect on COVID-19 Polymerase chain reaction(PCR) positive patients .
Detailed description
80 Patients with positive nasopharyngeal swab PCR for COVID-19 which were not hypoxic but showed computed tomography involvement compatible with COVID-19 admitted in ward (not in Intensive care unit) included and randomized in to two groups. All patients received standard treatment protocol including essential minerals, vitamins as antioxidants, antibiotics and Kaletra while in one randomly assigned group colchicine would be added.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Colchicine Tablets | 1.5 mg loading then 0.5 mg BID P.O |
Timeline
- Start date
- 2020-03-20
- Primary completion
- 2021-01-01
- Completion
- 2021-01-30
- First posted
- 2020-04-24
- Last updated
- 2022-01-28
Locations
2 sites across 1 country: Iran
Source: ClinicalTrials.gov record NCT04360980. Inclusion in this directory is not an endorsement.